منابع مشابه
Pyroptotic cells externalize eat-me and release find-me signals and are efficiently engulfed by macrophages.
Pathogenic intracellular bacteria often hijack macrophages for their propagation. The infected macrophages release IL-1β and IL-18 and simultaneously commit suicide, which is called pyroptosis; both responses require caspase-1. Here, we found that pyroptotic cells induced by microbial infection were efficiently engulfed by human monocytic THP-1-cell-derived macrophages or mouse peritoneal macro...
متن کاملFind-me and eat-me signals in apoptotic cell clearance: progress and conundrums
Everyday we turnover billions of cells. The quick, efficient, and immunologically silent disposal of the dying cells requires a coordinated orchestration of multiple steps, through which phagocytes selectively recognize and engulf apoptotic cells. Recent studies have suggested an important role for soluble mediators released by apoptotic cells that attract phagocytes ("find-me" signals). New in...
متن کاملBeginnings of a good apoptotic meal: the find-me and eat-me signaling pathways.
Prompt and efficient clearance of apoptotic cells is necessary to prevent secondary necrosis of dying cells and to avoid immune responses to autoantigens. Recent studies have shed light on how apoptotic cells through soluble "find-me" signals advertise their presence to phagocytes at the earliest stages of cell death. Phagocytes sense the find-me signal gradient, and in turn the presence of dyi...
متن کامل'Like me, want me, buy me, eat me': relationship-building marketing communications in children's magazines.
OBJECTIVE Television, Internet and print media are saturated with advertisements for unhealthy food that use marketing tactics aimed to build long-term brand loyalty and 'relationships' with children. While research in this area has largely focused on television, the current study examines children's responses to relationship-building marketing communications found in popular children's magazin...
متن کاملFind Me a Hash
W e're accustomed to hearing about the unreasonable effectiveness of mathematics, delightful—and unex-pected—applications of theory to the real world. In the world of the In-ternet, we've seen it in the use of number theory in public-key cryptography (the Diffie-Hellman system , the RSA algorithm, elliptic curve cryptosys-tems), in the utilization of graph theory in network design. In the world...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nature Reviews Immunology
سال: 2016
ISSN: 1474-1733,1474-1741
DOI: 10.1038/nri.2016.23